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This metabolic change can lead to mitochondrial alterations and, potentially, the inability of tumor cells to fully metabolize KBs as a source of energy and useful metabolic intermediates (29)

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Following incubation, extracts were centrifuged at 12,700 RPM for 10 min at 4 °C, and 80 µL of the resulting supernatant was transferred to fresh tubes for lipidomic analysis