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The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

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The insulating role of the myelin sheath is essential for Demyelination is the loss or deterioration of the myelin sheath and occurs in neurogenerative autoimmune diseases like Guillain-Barre and multiple sclerosis (MS)