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Results Etamicastat decreases blood pressure in mice with germ line deletion of D 2 R or renal-silenced D 2 R Systolic blood pressure measured under anesthesia was higher in D 2 −/− mice than in D 2 +/+ littermates treated with vehicle (122 ± 1 vs

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Future studies will need to carefully examine a potential gender difference and plausible mechanisms for such difference