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On allergies: there are no published case reports of allergic contact dermatitis to this ingredient, and one review notes camellia leaf and flower extracts are used topically without reported irritation issues

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The lactylation of K62 on pyruvate kinase M2 (PKM2), a crucial enzyme in glycolysis, inhibits its transition from tetramer to dimer and enhances its pyruvate kinase activity, thereby suppressing inflammatory metabolic adaptation in pro-inflammatory macrophages