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In addition to these effects, the possible simultaneous healing (stable gastric pentadecapeptide BPC 157, along with both NOS-blockade, L-NAME, and NOS-substrate L-arginine application[1]) would define the esophagogastric anastomosis healing, define esophagitis and gastric defects healing, rescue “sphincter” pressure at the site of anastomosis and preserve pyloric sphincter pressure, as a new NO-system related phenomenon