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OL-5, Lactobacillus plantarum Mut-7, and Lactobacillus plantarum Dad-13, have been found to exhibit higher intracellular uricase activity, further emphasizing the role of gut microbiota in UA metabolism

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936 By inducing the expression of D-fructose-6-phosphate amidotransferase 1 in adjacent renal TECs, the flux of hexosamine biosynthesis pathway increases, and the level of BACH2 o-glycosylation modification rises, inhibiting its ubiquitination degradation